RACK1: GNB2L1 Fusion Protein
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. RACK1 (receptor for activated protein kinase C 1), encoded by GNB2L1 gene, is a 317 amino acid guanine nucleotide-binding protein subunit beta-2-like 1 protein which is involved in the recruitment, assembly and/or regulation of a variety of signaling molecules, it contains 7 WD-repeats and is implicated in various protein interaction activities.
RACK1 is a component of the 40S ribosomal subunit involved in translational repression. Recent finding suggests that RACK1 may be a new promising diagnosis biomarker and therapeutic target for non-small-cell lung cancer (NSCLC).
Reconstitute at 0.25 µg/μl in 200 μl of sterile water for short term storage.
Reconstitution with 200 μl of 50% glycerol solution is recommended for longer term storage (see Stability and Storage for details).
If a different concentration is needed for your needs, please adjust the reconstitution volume as needed (please note: the ion concentration of the final solution will vary depending on the volume used).
Note: Centrifuge vial before opening. When reconstituting, gently pipette and wash the sides of the vial to ensure complete recovery of the protein in solution.